Gi Treatment Center
Opioid-Induced Constipation
Opioid pain medicines, such as Vicodin, Codeine, Dilaudid, Duragisic, and Norco, among others, can cause constipation by slowing down the intestines. This is called Opioid-Induced constipation, or OIC. Management of OIC can be complex and the best treatment depends on many factors. People with OIC should have an informed discussion with their doctor to develop an effective treatment plan.
FDA-Approved OIC Therapies
Amitiza®lubiprostone
Amitiza can help reduce constipation caused by opioid pain medications. It works by promoting fluid secretion into the intestines to aid in passing of stool.
Movantik®naloxegol
Movantik can help reduce constipation caused by opioid pain medications. When opioids bind to certain receptors in the intestines, it causes constipation. Movantik works by blocking the opioids from binding in the intestines.
Relistor®methylnaltrexone
Relistor can help reduce constipation caused by opioid pain medications. When opioids bind to certain receptors in the intestines, it causes constipation. Relistor works by blocking the opioids from binding in the intestines.
Symproic®naldemedine
Symproic can help reduce constipation caused by opioid pain medications. When opioids bind to certain receptors in the intestines, it causes constipation. Symproic works by blocking the opioids from binding these receptors in the intestines.
